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J. Krejci, P. Hude, E. Ozabalova, H. Poloczkova, D. Mlejnek, T. Freiberger, E. Nemcova, K. Benesova, J. Jarkovsky, L. Spinarova, P713
Significance of the viral presence in the myocardium on left ventricular systolic function and prognosis in recent onset dilated cardiomyopathy, European Heart Journal, Volume 38, Issue suppl_1, August 2017, ehx501.P713, https://doi.org/10.1093/eurheartj/ehx501.P713 - Share Icon Share
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Introduction: There are controversial data about the significance of the viral presence in the myocardium in recent onset dilated cardiomyopathy (RODCM). Furthermore, there were changes in the viral spectrum over time. Currently, parvovirus B19 (PVB19) marked prevalence is seen what distinctly contrasts with the situation in the past.
Purpose: To evaluate the significance of the viral presence in the myocardium on the development of left ventricular ejection fraction (LVEF) in 1-year follow-up and on the presence of combined endpoint in 5-year follow-up.
Patients and methods: 212 RODCM patients, 166 of them were males (78%), 46 females (22%). Mean age was 46.9±11.6 years, symptoms duration to diagnostic endomyocardial biopsy was 2.6±2.5 months, LVEF at baseline 24.1±7.1%, NYHA class 2.3±0.6. Combined mortality-morbidity endpoint was defined as the presence of death, resuscitation for cardiac arrest, adequate ICD discharge, heart transplantation or implantation of mechanical circulatory support, unscheduled hospitalization or non-planned outpatient visit for cardiovascular reason.