Extract

Backgroud: Transthoracic Doppler echocardiographically (TTDE) determined diastolic coronary low velocities (DCFV) are widely used for diagnosis of significant coronary artery stenosis (CAS). However, those factors influencing such DCFV are not well studied.

Aim: To evaluate of the effect of chronic total right coronary artery occlusion (CTRCAO) on the TTDE derived DCFV spectrum of the proximal left anterior descending coronary artery (LAD).

Methods: We enrolled 23 patients [16 male (70%), mean age 59±10 years] with CTRCAO and without stenosis of LAD and 13 [5 male (38%), mean age 62±10 years] age matched control subject without cardiovascular disease. All patients underwent a PCI attempt aiming the opening of the CTRCAO. All patients and control subjects underwent detailed TTDE at the beginning of the study. Patients with successful CTRCAO PCI underwent a repeated DCFV assessment by TTDE. DCFV were assessed by TTDE interrogating the proximal LAD. Peak (PDCVF) and velocity-time integrals (DCFVTI) of the DCFV spectrums were measured.

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