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Background: To evaluate the interventricular cardiac relationship, Doppler measurement of Qp/Qs by transthoracic echocardiography (TTE) has been used. It is complicated to do, however, and cannot evaluate interventricular relationship in the same cardiac phase. In recent echocardiographic examination, TAPSE (tricuspid annular plane of systolic excursion) and MAPSE (mitral annular plane of systolic excursion) have become widely used to assessment and quantification of the ventricular function. TAPSE and MAPSE can be evaluated using single echocardiographic view of four chamber view, but could not be evaluate in same cardiac cycle until the speckle tracking method introduce. To conquer this problem, we suppose to use the speckle tracking method. Speckle tracking method is an image analyzing technique to trace the local speckle pattern in B-mode of TTE. In practice, on simply placing ROI (region of interesting) to both the lateral tricuspid annulus and the lateral mitral annulus, based to apex, we will be able to evaluate TAPSE and MAPSE in the same cardiac cycle. We have hypothesized these; 1) the relationship of TAPSE and MAPSE in the same cardiac cycle could be a new surrogate indicator of interventricular functional relationship or dyssynchrony. 2) In AS patients, this relation could be different from healthy individuals.

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