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Wouter L’Hoyes, Sigurd Ghekiere, Thomas Rosseel, Answer: Acute dyspnoea with an unusual mass in the right ventricle, European Heart Journal. Acute Cardiovascular Care, Volume 12, Issue 4, April 2023, Page 281, https://doi.org/10.1093/ehjacc/zuac167
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Answer
What is the most likely diagnosis?
Infective endocarditis
Papillary fibroelastoma
Cyanoacrylate embolism
Thromboembolism
Explanation
Chest computed tomography angiogram showed dense, bilateral pulmonary embolism compatible with cyanoacrylate remnants which is used to obliterate varices. Cyanoacrylate is a monomer, which polymerizes fast when in contact with blood to form a strong glue. There are already clues to the aetiology of the mass on transthoracic echocardiography (Figure 1 and see Supplementary material online, Videos S1–S4). A history of drug abuse is a risk factor for endocarditis of the tricuspid valve, but vegetations tend to be irregular shaped with myocardial like grey scale. Furthermore, they are typically attached on the low-pressure side of atrioventricular valves. A papillary fibroelastoma is mostly localized downstream and would display a well-demarcated border with digitations but will rarely exceed a size of 3 cm as seen in this case (Figure 1A and B and see Supplementary material online, Videos S1 and S2), making it less plausible.1 A thrombus is less likely because it is frequently multi-lobulated and hypoechogenic in the acute phase.

Echocardiography images of cyanoacrylate embolism. (A) Parasternal short axis view showing a spherical, regular-shaped mass attached to the sub-valvular tricuspid apparatus with a filiform extension up to 5 cm. (B) Parasternal short axis view showing the extension of the mass through the ventricular outflow tract towards the pulmonary artery. (C) Apical five-chamber view showing a spherical mass with density greater than the adjacent endocardium.
Supplementary material
Supplementary material is available at European Heart Journal: Acute Cardiovascular Care online.
Funding
None declared.
Data availability
The data underlying this article will be shared on reasonable request to the corresponding author.
Reference
Author notes
Wouter L’Hoyes and Sigurd Ghekiere contributed equally to the study.
Conflict of interest: None declared.
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