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Young Investigator Award - Oral Abstract Session: Monday, 22 October 2012 - 08:30 - 10:00, European Heart Journal. Acute Cardiovascular Care, Volume 1, Issue 1_suppl, 1 October 2012, Pages 98–101, https://doi.org/10.1177/2048872612461726f
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Extract
277 Rapid rule out of acute myocardial infarction using undetectable levels of high-sensitive cardiac troponins
M Rubini Gimenez, R Hoeller, R Twerenbold, S Sou, M Mueller, R Ziller, K Murray, T Reichlin, T Mosimann, C Mueller
University Hospital Basel, Department of Cardiology, Basel, Switzerland
Purpose
The aim of this study was to examine whether undetectable levels of high-sensitive cardiac Troponin T (hs-cTnT) and I (hs-cTnI) can be used as a single variable to rule out the diagnosis of acute myocardial infarction (AMI) at presentation to the emergency department (ED).
Methods
In an ongoing prospective, international, multicenter study we measured hs-cTnT (Roche) and hs-cTnI using two different precommercial prototype assays (Siemens and Beckmann & Coulter) in consecutive patients presenting to the ED with acute chest pain. The final diagnoses of AMI were adjudicated by two independent cardiologists using all available data including hs-cTnT levels. Patients were followed during a mean period of 23 months.
- acute coronary syndromes
- myocardial infarction, acute
- atrial fibrillation
- cardiac myocytes
- st segment elevation myocardial infarction
- syncope
- levosimendan
- endothelial cells
- reperfusion therapy
- physiologic reperfusion
- awards and prizes
- emergency service, hospital
- hospitals, university
- patient prognosis
- timi grading system
- causality
- cardiac troponin measurement
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