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Jean-Marc Costa, Françoise Botterel, Odile Cabaret, Françoise Foulet, Catherine Cordonnier, Stéphane Bretagne, Association Between Circulating DNA, Serum (1→3)-β-d-Glucan, and Pulmonary Fungal Burden in Pneumocystis Pneumonia, Clinical Infectious Diseases, Volume 55, Issue 2, 15 July 2012, Pages e5–e8, https://doi.org/10.1093/cid/cis412
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Abstract
Circulating Pneumocystis jirovecii DNA and (1→3)-β-d-glucan determined in 70 serum samples from immunocompromised patients were compared to fungal load in bronchoalveolar lavage fluids assessed using quantitative polymerase chain reaction. Both serum biomarkers are influenced by pulmonary fungal load, which should be taken into account when diagnosing Pneumocystis infection.
© The Author 2012. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: [email protected].
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