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Christoph Pöhlmann, Johannes Schetelig, Ulrike Reuner, Martin Bornhäuser, Thomas Illmer, Alexander Kiani, Gerhard Ehninger, Enno Jacobs, Jacques Rohayem, Cidofovir and Foscarnet for Treatment of Human Herpesvirus 6 Encephalitis in a Neutropenic Stem Cell Transplant Recipient, Clinical Infectious Diseases, Volume 44, Issue 12, 15 June 2007, Pages e118–e120, https://doi.org/10.1086/518282
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Abstract
We report a stem cell transplant recipient who developed human herpesvirus 6 encephalitis. Human herpesvirus 6 load indicated massive intrathecal viral replication. Administration of cidofovir followed by foscarnet was associated with total clearance of human herpesvirus 6 infection. Cidofovir and foscarnet combination therapy may be beneficial for reducing mortality of (neutropenic) stem cell transplant recipients with human herpesvirus 6 encephalitis.