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In This Issue, Clinical Infectious Diseases, Volume 43, Issue 7, 1 October 2006, Page i, https://doi.org/10.1086/507844
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Traveler's diarrhea and irritable bowel syndrome (IBS) (Stermer et al., pp. 891–901). Four-hundred and five travelers completed a study investigating the influence of traveler's diarrhea on the risk of development of IBS. When assessed 6 to 7 months after repatriation, traveler's diarrhea was associated with a 5-fold increase in the risk of developing IBS. Abdominal pain, duration of diarrhea, and female sex seemed to be predisposing factors.
Etiology of childhood diarrhea (Klein et al., pp. 807–13). A prospective cohort study involving patients with diarrhea presenting to a large regional pediatric emergency department examined stool samples for potential diarrheal pathogens, including bacteria, viruses, and parasites. Nearly one-half of the patients had a definite or plausible pathogen in their stools. The authors were unable to develop a model for identification of patients in whom a stool culture would be positive that was substantially more accurate than physician judgment.
Prophylactic versus preemptive therapies for preventing posttransplantation cytomegalovirus disease with ganciclovir (Small et al., pp. 869–80). Meta-analyses of prophylactic and preemptive prevention strategies using ganciclovir showed the 2 strategies to be about equally effective for the prevention of disease due to cytomegalovirus infection.
