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Vivian H. Chu, Daniel J. Sexton, Christopher H. Cabell, Reller L. Barth, Paul A. Pappas, Rakesh K. Singh, Vance G. Fowler, Corey G. Ralph, Olcay Aksoy, Christopher W. Woods, Repeat Infective Endocarditis: Differentiating Relapse from Reinfection, Clinical Infectious Diseases, Volume 41, Issue 3, 1 August 2005, Pages 406–409, https://doi.org/10.1086/431590
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Abstract
Repeat infective endocarditis due to the same species can represent relapse of the initial infection or a new infection. We used time-based clinical criteria and pulsed-field gel electrophoresis–based molecular criteria to classify 13 cases of repeat infective endocarditis as either relapse or reinfection. The agreement between clinical and molecular criteria was imperfect (agreement in 10 [77%] of 13 cases).