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John R. Wingard, Antifungal Chemoprophylaxis after Blood and Marrow Transplantation, Clinical Infectious Diseases, Volume 34, Issue 10, 15 May 2002, Pages 1386–1390, https://doi.org/10.1086/340263
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Abstract
Invasive fungal infections are common and deadly in recipients of blood and marrow transplants. Current diagnostic techniques do not allow accurate early diagnosis, especially of infection with mould pathogens, and delays in diagnosis are associated with treatment failure. This lack of early diagnosis has provided the impetus for the development of antifungal prophylaxis. Fluconazole prophylaxis is highly effective for the control of invasive yeast infections and associated with few breakthrough infections. The development of antimould prophylaxis in this patient population is a high priority.