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Robert A. Bonomo, Multiple Antibiotic-resistant Bacteria in Long-term-care Facilities: An Emerging Problem in the Practice of Infectious Diseases, Clinical Infectious Diseases, Volume 31, Issue 6, December 2000, Pages 1414–1422, https://doi.org/10.1086/317489
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Abstract
Long-term-care facilities (LTCFs) are becoming a major component of the health care delivery system. The management of infections with antibiotic-resistant bacteria in elderly patients in LTCFs is presenting new challenges to our current therapeutic armamentarium. Among the enteric bacilli, resistance to ceftazidime, β-lactam/β-lactamase-inhibitor combinations, and trimethoprim-sulfamethoxazole present the foremost problems. Quinolone-resistant gram-negative and gram-positive bacteria are increasing in frequency because of the widespread use of these agents in empirical treatment. Among the resistant gram-positive organisms, methicillin-resistant Staphylococcus aureus, penicillin-resistant pneumococci, and vancomycin-resistant enterococci are the most feared pathogens. Education, antibiotic control measures, and fundamental epidemiological and scientific research are advocated as important preventive measures.
- antibiotics
- antibiotic resistance, bacterial
- bacillus
- ceftazidime
- communicable diseases
- delivery of health care
- gram-positive bacteria
- internship and residency
- lactams
- long-term care
- nursing homes
- penicillin resistance
- pneumococcal infections
- quinolones
- trimethoprim-sulfamethoxazole combination
- infections
- bacteria
- pathogenic organism
- older adult
- methicillin-resistant staphylococcus aureus
- medical residencies
- microbial colonization
- vancomycin-resistant enterococcus
- prevention