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Henry M. Feder, Rakesh K. Goyal, Peter J. Krause, Acyclovir-Induced Neutropenia in an Infant with Herpes Simplex Encephalitis: Case Report, Clinical Infectious Diseases, Volume 20, Issue 6, June 1995, Pages 1557–1559, https://doi.org/10.1093/clinids/20.6.1557
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Abstract
A newborn infant whose condition was diagnosed as herpes simplex encephalitis and who had subsequent recurrences of skin disease had repeated episodes of neutropenia while receiving therapy with intravenous (30 mg/[kg · d]) or oral (30 mg/[kg · d]) acyclovir. The neutropenia did not recur when the dosage of oral acyclovir was reduced to 10 mg/(kg · d). This case represents the first well-documented report of acyclovir-induced neutropenia.
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© 1995 by The University of Chicago
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