-
Views
-
Cite
Cite
Charles D. Bluestone, Current Therapy for Otitis Media and Criteria for Evaluation of New Antimicrobial Agents, Clinical Infectious Diseases, Volume 14, Issue Supplement_2, June 1992, Pages S197–S203, https://doi.org/10.1093/clinids/14.Supplement_2.S197
- Share Icon Share
Abstract
Otitis media is the most commonly diagnosed disease in infants and children in the United States. For routine empirical treatment of uncomplicated acute otitis media, amoxicillin is the drug of choice. Persistence of signs and symptoms of infection during antimicrobial therapy calls for a change to an antibiotic effective against β-lactamase-producing bacteria (e.g., trimethoprim-sulfamethoxazole, amoxicillin/clavulanate, or one of the newer oral cephalosporins) or performance of tympanocentesis/myringotomy or both. The most common nonsurgical and surgical methods currently employed for prevention of frequent recurrences are antimicrobial prophylaxis, myringotomy with insertion of a tympanostomy tube, and adenoidectomy. For patients who have otitis media with effusion for which treatment is indicated, antimicrobial agents have been shown to be effective; amoxicillin is preferred as initial therapy. Guidelines for evaluating new antimicrobial agents in the treatment of otitis media are presented in this report.
- amoxicillin
- antibiotics
- antibiotic prophylaxis
- cephalosporins
- otitis media, acute
- adenoidectomy
- amoxicillin-potassium clavulanate combination
- child
- infant
- otitis media
- otitis media with effusion
- surgical procedures, operative
- trimethoprim-sulfamethoxazole combination
- infections
- bacteria
- guidelines
- antimicrobials
- tympanostomy
- myringotomy tubes
- prevention