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15.1 A Simple Model of the Determinants of Research Expenditure at the Disease Level 15.1 A Simple Model of the Determinants of Research Expenditure at the Disease Level
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15.1.1 Multiple Indicators of Incidence 15.1.1 Multiple Indicators of Incidence
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15.1.2 Differences in Research Productivity (Scientific Opportunity) across Diseases 15.1.2 Differences in Research Productivity (Scientific Opportunity) across Diseases
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15.2 Data Sources and Methods 15.2 Data Sources and Methods
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15.2.1 Data on Government-Funded Research Expenditures, by Disease 15.2.1 Data on Government-Funded Research Expenditures, by Disease
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15.2.2 Data on Disease Burden, Prevalence, and Incidence 15.2.2 Data on Disease Burden, Prevalence, and Incidence
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Premature Mortality Data Premature Mortality Data
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Data on Prevalence of Selected Chronic Conditions Data on Prevalence of Selected Chronic Conditions
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15.3 Preliminary Estimates 15.3 Preliminary Estimates
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15.3.1 Premature Mortality 15.3.1 Premature Mortality
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15.3.2 Prevalence and Severity of Chronic Conditions in the (Living) Population 15.3.2 Prevalence and Severity of Chronic Conditions in the (Living) Population
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15.4 Summary 15.4 Summary
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References References
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15 The Allocation of Publicly Funded Biomedical Research
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Published:April 2001
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Abstract
In the last century, the average health of the American people has improved dramatically. The mean life expectancy of Americans has increased almost twenty years, or two years per decade, since the turn of the century. Just from 1979 to 1988, the age-adjusted mortality rate declined 7.2 percent. An important part of this enormous progress in health is probably due to large private and public investments in biomedical research. In 1993, research and development (R&D) in the health care sector accounted for 18 percent of total R&D expenditure in the United States. The National Institutes of Health (NIH) administer about 80 percent of federal health R&D and places a high priority on funding basic research. This chapter describes a simple theoretical model of the allocation of the applied component of public biomedical research expenditure — the approximately 50 percent of expenditure that is of direct, near-term relevance to specific diseases — and presents some empirical evidence about the determinants of this budget allocation.
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