Extract

PATHOLOGY OF SKELETAL MUSCLE. 2nd edition.
 By Stirling Carpenter and George Karpati.
 2001. Oxford: Oxford University Press.
 Price: £140. Pp. 672. ISBN 0‐19‐506364‐3.

A lengthy 17 years after its distinguished predecessor, a second edition of Pathology of Skeletal Muscle has now been published. For most of those years I, like many other pathologists, have relied heavily on the first edition for advice on the interpretation of muscle biopsies. To my mind, the descriptions of normal and abnormal structures and their significance, and the clarity and comprehensiveness of the illustrations have not been bettered in any other myopathology text. It was therefore with high expectation that I ordered the second edition, without waiting to see the reviews or even having had a chance to look through it.

The page format is larger and the arrangement of the references different (they are now placed at the end of each topic rather than grouped together at the end of the chapter), but most of the original illustrations are still there and the basic framework has altered very little since the first edition. The majority of changes in the new edition take the form of supplements to the text. These reflect the substantial advances that have occurred over the past decade or so in our understanding of the molecular processes involved in the development of muscle and in the aetiology and pathogenesis of muscular diseases, genetic diseases in particular.

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