Statistical Theory and Methods for Evolutionary Genomics
Published:
04 November 2010
Online ISBN:
9780191594762
Print ISBN:
9780199213269
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Contents
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6.1 Coding sequence divergence vs expression divergence 6.1 Coding sequence divergence vs expression divergence
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6.2 Regulatory motif divergence vs expression divergence between duplicates 6.2 Regulatory motif divergence vs expression divergence between duplicates
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6.3 Gene duplication and expression diversification 6.3 Gene duplication and expression diversification
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6.4 Expression divergence and retention of duplicate genes 6.4 Expression divergence and retention of duplicate genes
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6.5 Evolutionary distance of expression divergence 6.5 Evolutionary distance of expression divergence
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6.6 Rate of expression divergence between yeast duplicate genes 6.6 Rate of expression divergence between yeast duplicate genes
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6.7 Asymmetric expression evolution after gene duplications 6.7 Asymmetric expression evolution after gene duplications
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6.8 Concluding remarks 6.8 Concluding remarks
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Chapter
6 6 Expression between Duplicate Genes: Genome‐Wide Analysis
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Pages
113–126
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Published:04 November 2010
Cite
Gu, Xun, '6 Expression between Duplicate Genes: Genome‐Wide Analysis', Statistical Theory and Methods for Evolutionary Genomics (Oxford , 2010; online edn, Oxford Academic, 1 Jan. 2011), https://doi.org/10.1093/acprof:oso/9780199213269.003.0006, accessed 27 July 2026.
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Abstract
Expression divergence between duplicate genes has long been a subject of great interest to geneticists and evolutionists. Ohno proposed that expression divergence is the first step in the functional divergence between duplicate genes and thereby increases the chance of retention of duplicate genes in a genome. Further, advances in molecular biology in the 1970s and 1980s provided a much better understanding of the molecular basis of expression divergence between duplicate genes. The availability of completely sequenced genomes and microarray gene expression and other functional genomic data have stimulated many studies on these questions. This chapter introduces these results.
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