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Familial and genetic factors Familial and genetic factors
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Searching for biological markers Searching for biological markers
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Abnormalities of brain structure Abnormalities of brain structure
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Abnormalities of brain function Abnormalities of brain function
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Problems with the interpretation of studies of functional imaging Problems with the interpretation of studies of functional imaging
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Cite
Abstract
‘Biological factors’ explores research into the cause of schizophrenia. Some have sought a biological basis for the disorder, while others have looked for social or psychological causes. In recent years, however, the emphasis has been upon biological causes. Twin and adoption studies provide good evidence that genetic factors play a major role in the development of schizophrenia, but it is clear that this role is not absolute. Several genes may interact with one another and with environmental factors to influence susceptibility to schizophrenia. Neuropathological and neuro-imaging studies have sought a relationship between the symptoms or course of the illness and structural brain changes, but consistent findings have not been shown.
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