Ketogenic Diet and Metabolic Therapies: Expanded Roles in Health and Disease (2 edn)
Ketogenic Diet and Metabolic Therapies: Expanded Roles in Health and Disease (2 edn)
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Abstract
Ketogenic diets have been treating epilepsy for over 100 years, and in recent decades the awareness and applications of ketogenic therapies have expanded dramatically. The second edition of Ketogenic Diets and Metabolic Therapies: Expanded Roles in Health and Disease honors the major milestone of entering the second century of metabolic therapies. This new edition builds on the original edited volume with updated content and entirely new chapters. Leaders in the field (Susan A. Masino, PhD, Eric H. Kossoff, MD, Jong M. Rho, MD, Detlev Boison, PhD, and Dominic P. D’Agostino, PhD) assembled some of the latest research on mechanisms, established and emerging applications, metabolic alternatives, and implications for health and disease.
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Front Matter
- 1 The 100th Anniversary of the Ketogenic Diet: Local and Global Perspectives
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Section I Ketogenic Diet for Epilepsy in the Clinic
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2
Overview: Ketogenic Diets and Pediatric Epilepsy: An Update
Eric Kossoff
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3
Alternative Ketogenic Diets
Elizabeth Neal
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4
Ketogenic Diet Therapies in Adults: History, Demand, and Results
Emily L. Johnson andMackenzie C. Cervenka
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5
How Do You Implement the Diet?
A. G. Christina Bergqvist
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6
GLUT1 Deficiency Syndrome and the Ketogenic Dietary Therapies
Joerg Klepper
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7
Ketogenic Diet in Established Epilepsy Indications
Ann M. Bergin
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8
Ketogenic Diet for Other Epilepsies
David T. Hsieh andElizabeth A. Thiele
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9
The Ketogenic Diets in Genetic Generalized Epilepsy Syndromes
Sudha Kilaru Kessler
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10
Ketogenic Diet Therapy for Infants
Elles J. T. M. van der Louw and others
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11
Ketogenic Diet in Status Epilepticus
Rima Nabbout
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12
Preventing Side Effects and Diet Discontinuation
Cherie L. Herren andRana R. Said
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2
Overview: Ketogenic Diets and Pediatric Epilepsy: An Update
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Section II Ketogenic Diet: Emerging Clinical Applications and Future Potential
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13
Overview: Expanded Uses of Ketogenic Therapies
Jong M. Rho
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14
Metabolism-Based Treatments for Managing Cancer: Scientific Rationale
Thomas N. Seyfried and others
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15
Ketogenic Diet as Adjunctive Therapy for Malignant Brain Cancer
Adrienne C. Scheck andNelofer Syed
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16
Ketogenic Diet, Social Behavior, and Autism: Insights from Animal Models
Ning Cheng and others
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17
Ketotherapeutics to Rescue Brain Energy Deficits: An Emerging Strategy to Delay Cognitive Decline in Alzheimer’s Disease
Étienne Myette-Côté and others
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18
Ketogenic Diet and Ketones for Improving Neurologic Outcomes after Acute Neurotrauma
Oscar Seira and others
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19
Ketogenic Diets and Neuroinflammation
David Ruskin and others
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20
The Ketogenic Diet in the Treatment of Schizophrenia
Zoltán Sarnyai and others
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21
The Ketogenic Diet and the Gut Microbiome
Chunlong Mu and others
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13
Overview: Expanded Uses of Ketogenic Therapies
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Section III Ketogenic Diet in the Laboratory
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22
Overview: Ketogenic Diet in the Laboratory: Progress on Models and Mechanisms
Detlev Boison
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23
Ketogenic Diet and PPARγ
Timothy A. Simeone
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24
Ketogenic Diet and Adenosine in Epilepsy: Models and Mechanisms
Masahito Kawamura
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25
Ketogenic Diet and Epigenetic Mechanisms of Epileptogenesis
Madhuvika Murugan and others
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26
Ketogenic Diet, Aging, and Neurodegeneration
Kui Xu and others
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27
Metabolic Seizure Resistance via BAD and KATP Channels
Juan Ramón Martínez-François and others
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28
Lactate Dehydrogenase: A Novel Metabolic Target
Nagisa Sada andTsuyoshi Inoue
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29
Effects of the Ketogenic Diet on the Blood–Brain Barrier
Damir Janigro
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30
Metabolic and Redox Alterations by Ketogenic Diets
Derek Johnson andManisha Patel
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31
Nicotinamide Adenine Dinucleotide as a Central Mediator of Ketogenic Therapy
Marwa Elamin and others
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22
Overview: Ketogenic Diet in the Laboratory: Progress on Models and Mechanisms
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Section IV Ketone-Based Metabolism: General Health and Metabolic Alternatives
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32
Overview: Ketone-Based Metabolism—General Health and Metabolic Alternatives
Dominic P. D’Agostino
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33
Ketone Supplementation for Health and Disease
Angela M. Poff and others
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34
Neuroprotective and Behavioral Benefits of Exogenous Ketone Supplementation-Evoked Ketosis
Zsolt Kovacs and others
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35
Amino Acids in the Treatment of Neurologic Disorders
Adam L. Hartman
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36
Identifying the Molecular Mechanism of the MCT (Ketogenic) Diet
Matthew C. Walker andRobin S. B. Williams
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37
Triheptanoin in Epilepsy and Beyond
Karin Borges
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38
Antiseizure and Antiepileptic Effects of Glycolysis Inhibition with 2-Deoxyglucose
Carl E. Stafstrom and others
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39
Low-Carbohydrate, Ketogenic Diets for the Treatment of Type 2 Diabetes and Obesity
Eric C. Westman and others
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40
Intermittent Exogenous Ketosis for Athletic Performance, Recovery, and Adaptation
Brianna J. Stubbs andPeter Hespel
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41
Advancing the Awareness and Application of Ketogenic Therapies Globally: The Charlie Foundation for Ketogenic Therapies and Matthew’s Friends
Beth Zupec-Kania and others
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32
Overview: Ketone-Based Metabolism—General Health and Metabolic Alternatives
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End Matter
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