Cognitive Dimensions of Major Depressive Disorder
Cognitive Dimensions of Major Depressive Disorder
Cato Chair and Head of Department of Psychiatry
Professor of Cognitive Neuroscience
Cite
Abstract
The lifetime prevalence of 15% for major depressive disorder (MDD) within the general population is among the highest among all mental disorders. MDD is also one of the leading causes of disability and has been estimated to affect 300 million people worldwide. Clinical, functional, and biological correlates of MDD are frequently investigated almost exclusively based on research that defines depression as a categorical disorder assessed by established diagnostic instruments. Given the phenotypic and biological heterogeneity of depression, a refocus of the clinical phenotype of depression is required and widely recommended. Cognitive dimensions of depression have long been implicated in the nature of depression as a disorder that is characterized by typically impaired cognitive and emotional processes. The systems of cognitive function, emotion processing, and social cognitive processing are regarded as comprehensively describing large parts of the clinical symptoms as well as the pathophysiology of the brain-based disorder of depression. The focus on the above cognitive and emotional dimensions of depression offers promising extended and novel diagnostic and treatment approaches ranging from pharmacological to psychological interventions targeting those dimensions of depression. This book aims to provide an improved understanding of the characteristics of the dimensional approach of depression, focusing on the cognitive, emotional, and social cognitive processes.
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Front Matter
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1
Functional and Psychosocial Consequences of Major Depressive Disorder
Tracy L. Greer andJeethu K. Joseph
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2
Opportunities and Challenges of the Phenotypic Heterogeneity of Major Depressive Disorder
Koen Demyttenaere
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3
Major Depressive Disorder as a Disorder of Cognition
Muzaffer Kaser andBarbara J. Sahakian
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4
Cognitive Dysfunction as a Symptom Dimension Across Major Psychiatric Disorders
Zihang Pan andRoger S. McIntyre
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5
Clinical and Functional Characteristics of Cognitive Dysfunction in Major Depressive Disorder
Maria Serra-Blasco andRaymond W. Lam
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6
The Assessment of Cognitive Dysfunction in Major Depressive Disorder
John E. Harrison
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7
Molecular Neurobiology of Cognitive Dysfunction in Major Depressive Disorder
Natalie T. Mills andBernhard T. Baune
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8
Clinical Characteristics of Emotional-Cognitive Dysfunction in Major Depressive Disorder
Thomas Beblo andLorenz B. Dehn
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9
Neurocircuitries of Emotion Processing Affected in Major Depressive Disorder
Anjali Sankar andCynthia H.Y. Fu
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10
The Neural Circuitry of Negative Bias, Oversensitivity to Negative Feedback, and Hyposensitivity to Reward in Major Depressive Disorder
Oliver J. Robinson
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11
Reward Processing in Adolescents with Depression
Georgia O’Callaghan andArgyris Stringaris
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12
Cognition-Related Brain Networks Underpin Cognitive, Emotional, and Somatic Symptom Dimensions of Depression
Genevieve Rayner
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13
Networks of Cognitive Processes: Functional and Anatomical Correlates of Cognition, Emotions, and Social Cognition
John D. Medaglia
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14
The Neurobiology of Emotion–Cognition Interactions
Thalia Richter and others
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15
Clinical Characteristics of Social Cognitive Processes in Major Depressive Disorder
Katharina Foerster and others
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16
Understanding of Self and Others: Neurobiological Underpinnings of Social Cognition
Franziska K. Goer andRebecca Elliott
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17
Emotional and Cognitive Consequences of Social Rejection: An Entry Door to Major Depression
Philippe Fossati and others
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18
Pharmacological Interventions for Cognitive Dysfunction in Major Depressive Disorder
Marco Solmi and others
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19
Psychological Interventions for Cognitive Dysfunction in Major Depressive Disorder
Claudia Woolf and others
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20
Can Non-Pharmacological Antidepressant Treatments Influence the Processing of Affective Information?
Alexander Kaltenboeck andCatherine Harmer
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21
Social Cognitive Deficits: Impact on Psychosocial Function and Novel Treatment Opportunities in Major Depressive Disorder
Michael Weightman andBernhard T. Baune
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End Matter
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