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Conflicts of interest: none declared.

Dear Editor, A 68‐year‐old man with a history of B‐cell lymphoma presented with liver failure and was started on etoposide and dexamethasone for presumed haemophagocytic lymphohistiocytosis. A painful rash developed 2 days after commencement of chemotherapy. On examination, dusky crusted papules were present in the inguinal folds. Histopathology revealed angioinvasive fungal organisms, and tissue culture confirmed the diagnosis of Scedosporium apiospermum. Only a limited number of cases of S. apiospermum localized to the skin have been reported in the literature.1  2 The patient was started on voriconazole with stabilization of his rash; however, he was transitioned to comfort care given his poor prognosis.

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