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H. Yang, A. Tong, Image Gallery: Xanthoma tuberosum, British Journal of Dermatology, Volume 176, Issue 4, 1 April 2017, Page e34, https://doi.org/10.1111/bjd.15326
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Funding sources: none.
Conflicts of interest: none declared.
Dear Editor, A 41‐year‐old man with primary aldosteronism presented with four nodules, one over each elbow and ankle, for 15 years (a). No family history of hypercholesterolaemia was revealed. The nodules gradually progressed in size despite well‐controlled hypercholesterolaemia with rosuvastatin. He reported no history of diabetes. The total cholesterol was 4·06 mmol L−1 (normal range 2·85–5·70), the triglyceride level was 1·19 mmol L−1 (0·45–1·70), low‐density lipoprotein cholesterol was 2·36 mmol L−1 (< 3·37), high‐density lipoprotein cholesterol was 1·25 mmol L−1 (93–1·81), glucose was 4·7 mmol L−1 (3·9–6·1) and uric acid was 386 mmol L−1 (210–416). Histological analysis of a biopsy specimen showed accumulation of large foam cells, and the diagnosis of tuberous xanthomas was confirmed (b; haematoxylin and eosin, original magnification × 200). The initial differential diagnoses, including ganglion cyst, lipoma and fibroma, were thus excluded.
