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S. Muramatsu, Y. Suga, Y. Mizuno, T. Hasegawa, Y. Komuro, Y. Kubo, S. Imakado, H. Ogawa, A Japanese case of naevoid basal cell carcinoma syndrome associated with segmental vitiligo, British Journal of Dermatology, Volume 152, Issue 4, 1 April 2005, Pages 812–814, https://doi.org/10.1111/j.1365-2133.2005.06504.x
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Sir, A 22‐year‐old Japanese man (patient 1) presented for clinical examination with his parents. He exhibited multiple brown–black lesions both on his face (Fig. 1a) and on his entire body (Fig. 1b) that had been evident from infancy. He also had pitting of the palms (Fig. 1c) and soles that had developed in the previous few years. Five years earlier, he had begun to develop a depigmented lesion with poliosis (white hair) on the left side of the first trigeminal area (Fig. 1a), and was diagnosed as having segmental‐type vitiligo by a dermatologist at another hospital.
His mother reported that he was mentally retarded due to a congenital hydrocephalus, which had been treated using a surgical shunt when he was 3 months old. Computed tomography revealed some intracranial calcifications of the falx cerebri, and two growing odontogenic keratocysts on the left side of the maxilla and mandible (Fig. 1d,e). Physical examination was otherwise normal, and standard haematological tests were negative or normal. According to the clinical criteria of Kimonis et al.1 we diagnosed our patient as having naevoid basal cell carcinoma syndrome (NBCCS).
