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B. Bartolomé, S. Córdoba, S. Nieto, J. Fernández‐Herrera, A. García‐Díez, Acute arsenic poisoning: clinical and histopathological features, British Journal of Dermatology, Volume 141, Issue 6, 1 December 1999, Pages 1106–1109, https://doi.org/10.1046/j.1365-2133.1999.03213.x
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Abstract
We report a woman with acute arsenic poisoning, who developed an erythroderma with vesicles and pustules after the ingestion of 8–16 g of sodium arsenite. Simultaneously, she presented a herpes simplex virus infection. Skin biopsies showed unique features which included multiple small pigment granules inside and outside the histiocytes. In our opinion, these findings are consistent with acute arsenic poisoning, and constitute the first histological description of this entity in skin.