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Joseph P. Hunstad, Marcaine® Induces Clinically Beneficial Analgesia in the Immediate Postoperative Period, Aesthetic Surgery Journal, Volume 17, Issue 4, July 1997, Pages 269–270, https://doi.org/10.1016/S1090-820X(97)80012-X
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I believe that Marcaine® can provide a significant clinical benefit to patients. However, I also recognize that the inappropriate use of this agent can result in terrible consequences. I administer Marcaine® after certain aesthetic procedures, and the effects are very impressive. To my knowledge it is the longest-acting local anesthetic, particularly when it is combined with epinephrine. I always use Marcaine® with epinephrine because this increases the longevity of the block's effectiveness, but more importantly, because it increases the block's safety by reducing the rate of absorption.
I administer Marcaine® after abdominoplasty procedures because I do very aggressive muscle plication, which creates a notable degree of discomfort. I perform all ab-dominoplasties on an outpatient basis, and the infiltration of Marcaine® minimizes the discomfort of these patients in the immediate postoperative period. I also infiltrate the entire surgical area with tumescent fluid, which is a very dilute, lidocaine-based local anesthetic that contains epinephrine. The Physicians' Desk Reference does not state that Marcaine® should not be used in combination With other agents, but rather that it cannot be recommended because of lack of sufficient data on this manner of using it.
