Extract

Brand: Ohtuvayre®

AHFS Classification: 48:34

Introduction

Ensifentrine is an inhibitor of phosphodiesterase 3 (PDE3) and phosphodiesterase 4 (PDE4).

Uses

Ensifentrine has the following uses:

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Dosage and Administration

General

Ensifentrine is available in the following dosage form(s) and strength(s): Inhalation suspension: 3 mg/2.5 mL aqueous suspension in unit-dose ampules.

Dosage

It isessentialthat the manufacturer’s labeling be consulted for more detailed information on dosage and administration of this drug. Dosage summary:

Adults

Dosage and Administration

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Cautions

Contraindications

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Warnings and Precautions

Acute Episodes of Bronchospasm

Ensifentrine should not be used for the relief of acute symptoms, i.e., as rescue therapy for the treatment of acute episodes of bronchospasm. Ensifentrine has not been studied in the relief of acute symptoms and extra doses should not be used for that purpose. The safety and effectiveness of ensifentrine for relief of acute symptoms have not been established. Acute symptoms should be treated with an inhaled, short-acting bronchodilator.

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