Abstract

Objective

To define awareness, treatment, and control of hypertension in adults in Southwest China and to investigate relevant personal characteristics, as well as antihypertensive drug use among patients with hypertension.

Methods

Data from a population-based high-risk cardiovascular screening study named China PEACE (Patient-Centered Evaluative Assessment of Cardiac Events) Million Persons Project in Southwest China, collected from January 2016 to December 2017, were used. Basic information, physical examination, and questionnaire were collected. In this population, hypertension was defined as systolic blood pressure (SBP) ≥140 mm Hg and/or diastolic blood pressure (DBP) ≥90 mm Hg, or self-reported antihypertensive medication use in the previous 2 weeks or history of hypertension. Hypertension awareness, treatment, and control were defined, respectively, among hypertensive adults as a self-reported diagnosis of hypertension, current use of antihypertensive medication, and blood pressure ≤140/90 mm Hg. The prevalence, awareness, treatment, and control rates of hypertension in subgroups were assessed, and the associations of hypertension management with individual characteristics were identified using mixed models. The number and pattern of medication use were also investigated.

Results

The sample contained 315,250 participants with a mean age of (55.2 ± 10.3) years, 38.5% of whom were males. The average blood pressure was 133.4/80.9 mm Hg, and 127,231 subjects had hypertension, of whom 42.3% were aware of their diagnosis, 27.8% were under antihypertensive medications treatment, and 8.9% achieved control. Women had higher awareness and treatment rates than men (P < 0.001). Age, income, education, diabetes, or previous cardiovascular events had a positive correlation, while alcohol use had a negative correlation with awareness, treatment, and control rates (all P < 0.05). Among patients under treatment, 86.8% took one anti-hypertensive drug and only 1.3% took three or more drugs. The most common drug used was calcium channel blockers (CCB; 49.0%). Angiotensin converting enzyme inhibitor /angiotensin receptor blocker plus CCB (35.7%) was the most common combination therapy.

Conclusion

Hypertension awareness, treatment, and control in community-dwelling residents are poor, and the proportion of drug combination therapy is low in Southwest China.

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