Abstract

In the superior cervical ganglia (SCG) binding site density of angiotensin II (ANG II) was higher in adult spontaneously hypertensive rats (SHR) (571 ± 29 fmol/mg protein) compared to that in the adult Wistar-Kyoto rat (WKY) (375 ± 9 fmol/mg protein, P < 0.05). The ANG II binding density was significantly decreased in the SCG of SHR (−59 %, P < 0.01) and of WKY (−39 % , P < 0.05) after unilateral preganglionic denervation (operated ν shamoperated ganglia). Part of t h e binding sites in the superior cervical ganglia may be present in or be associated to preganglionic nerves, and the number of these sites is higher in SHR. Am J Hypertens 1989;2:647-649

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