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Seiichi Shibasaki, Kazuomi Kario, Yoshio Matsui, Joji Ishikawa, Kazuo Eguchi, Satoshi Hoshide, Kazuyuki Shimada, P-689: Which reading of home blood pressure in an occasion is the most correlated with left ventricular hypertrophy?, American Journal of Hypertension, Volume 18, Issue S4, May 2005, Page 260A, https://doi.org/10.1016/j.amjhyper.2005.03.706
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Abstract
Left ventricular hypertrophy (LVH) is well recognized as an independent risk factor for cardiovascular events in hypertensive patients. There are reports indicating that LVH is more closely related to home blood pressure (HBP) than to office BP (OBP). In some guidelines for HBP measurement, it is recommended to repeat measurements in an occasion. However, which reading of HBP in an occasion should be used has not yet been clarified. We investigated which reading of HBP is the most correlated with left ventricular mass index (LVMI).
We enrolled 58 hypertensive outpatients (21 males and 37 females, 40–87 years old, 87.9% medicated) based on 2 consecutive OBPs (SBP≥140mmHg or DBP≥90mmHg) at two visits with at least 2 week interval, and asked them to measure 3 consecutive HBPs in two occasions daily, i.e., in the morning within 1 hour after waking-up and in the evening just before going to bed, for 14 days. At the third study visit, we measured 3 consecutive OBPs. HBP was measured and automatically stored with validated fully automated (electronic) device(Omron HEM-747IC). We compared correlation coefficient (r) between SBP averaged over for 14 days and LVMI, among 1st, 2nd and 3rd HBP readings in the morning and evening. We also compared the r between OBP and HBP.
The table summarizes the results (r-values and p-values). Higher correlation with LVMI was seen for morning HBP than for evening HBP. Among morning HBP, 2nd reading showed the highest correlation. OBP did not show significant correlation with LVMI.
Correlation coefficients between SBP and LVMI
| . | Morning . | Evening . | Office . |
|---|---|---|---|
| 1st reading | 0.340 (p = 0.009) | 0.207 (p = 0.119) | |
| 2nd reading | 0.357 (p = 0.006) | 0.208 (p = 0.117) | |
| 3rd reading | 0.341 (p = 0.009) | 0.213 (p = 0.109) | |
| Office | 0.167 (p = 0.215) |
| . | Morning . | Evening . | Office . |
|---|---|---|---|
| 1st reading | 0.340 (p = 0.009) | 0.207 (p = 0.119) | |
| 2nd reading | 0.357 (p = 0.006) | 0.208 (p = 0.117) | |
| 3rd reading | 0.341 (p = 0.009) | 0.213 (p = 0.109) | |
| Office | 0.167 (p = 0.215) |
Correlation coefficients between SBP and LVMI
| . | Morning . | Evening . | Office . |
|---|---|---|---|
| 1st reading | 0.340 (p = 0.009) | 0.207 (p = 0.119) | |
| 2nd reading | 0.357 (p = 0.006) | 0.208 (p = 0.117) | |
| 3rd reading | 0.341 (p = 0.009) | 0.213 (p = 0.109) | |
| Office | 0.167 (p = 0.215) |
| . | Morning . | Evening . | Office . |
|---|---|---|---|
| 1st reading | 0.340 (p = 0.009) | 0.207 (p = 0.119) | |
| 2nd reading | 0.357 (p = 0.006) | 0.208 (p = 0.117) | |
| 3rd reading | 0.341 (p = 0.009) | 0.213 (p = 0.109) | |
| Office | 0.167 (p = 0.215) |
In conclusion, these results suggest that HBP is more useful than OBP in evaluating LVH. Morning HBP is more useful than evening HBP, and furthermore, the second reading of morning HBP is more useful than the first and the third one of them in evaluating LVH.
