Search
Close
Search
Advanced Search
Search Menu
AI Discovery Assistant

Abstract

Cerebrovascular pathology, in comparison with cardiovascular diseases, has not been widely studied in renal transplant recipients (RTR). We here analize the etiopathogenic and clinical aspects as well as the outcome of stroke (S) in this special population.

We evaluated the clinical features and risk factors of 19 out of 404 RTR who suffered S after renal grafting, taking into account the following data: age, gender, time after renal transplantation, original nephropathy, previous stroke and also the well-known cardiovascular risk factors: tobacco smoking, dislipemia, hypertension (HT) and diabetes mellitus (DM). We also describe the nature of S, their localization, clinical outcome and time to death if it occurred.

There were 11 males and 8 females, average 49.8yr age, with an interval from RT to S of 52.1months in average (min: 3.41m- max: 87.82m; sd=25.55m). Eight out of the 19 RTR (42.1%) had suffered S previously to RT. Regarding to the classic cardiovascular risk factors, HT was prevalent in 100% of the cases, dislipemia in 68.4%, smoker condition in 26.3% and DM in 31.6% (interval: 23-63yr) of the patients. There were 7 cerebral hemorrhages and 12 ischemic S (7 of them were atherothrombotic). Localization was deep/basal ganglia in 10, superficial/lobar in 8, and the other one was placed in the brainstem. Nine out of 19 patients (47.36%) died within the 3 months following S, and S was the cause of death in seven out of these 9 patients (77.78%).

We conclude that: 1) HT was the most prevalent risk factor for S in the RTR 2) cerebral hemorrhage was more prevalent (36.84% of S) in RTR than in general population. 3) mortality after S is high in RTR (~50%). According to these conclusions, we think that we must do a great effort to optimize the control of HT in those patients (RTR) in order to prevent them from such disease paying an special attention to patients with diabetes and to patients with other manifestations of cardiovascular disease.

Stroke, Renal transplantation, Hypertension
This content is only available as a PDF.
© American Journal of Hypertension, Ltd. 2001
Topic:
Issue Section:
Abstracts
You do not currently have access to this article.
Download all slides