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T. Ikeda, T. Gomi, Y. Shibuya, T. Kosugi, K. Sekiya, M. Tanimoto, P-49: Morning rise in blood pressure associates with hypertensive cardiovascular complications, American Journal of Hypertension, Volume 14, Issue S1, April 2001, Pages 45A–46A, https://doi.org/10.1016/S0895-7061(01)01527-8
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Abstract
Blood pressure rise in early morning is considered as an important risk factor for vascular complication of hypertension. We examined the characteristics of hypertensive patients who had a blood pressure rise in the morning judged by self-measurement at home concerning to the hypertensive cardiovascular complications. 101 cases of untreated hypertensive patients (79 men and 38 women, 54.5 ± 11.1 years) were recruited to this study. Patients were instructed on how to measure their own blood pressures at home by nursing stuffs. Monitor used in this study was cuff-oscillometric devise (Omron HEM-737, Omron Corp., Tokyo), which were checked by connecting to the sphygmomanometer with a Y-connector at monthly clinic visits. Patients were asked to measure their home blood pressure in the morning within 30 minutes after awakening and in the evening just before going to bed. Subjects were divides to 2 groups according to the difference of systolic blood pressure between morning and evening (M-SBP-E-SBP); morning rise group (MR)=M-SBP-E-SBP ≥ 10mmHg and non-morning rise group (NMR)=M-SBP-E-SBP < ± 10mmHg. MR had a high left ventricular mass index (149 ± 37 vs 122 ± 21, p<0.001), serum creatinine (Cr, 0.88 ± 0.23 vs 0.75 ± 0.17 mg/dl) and urinary protein secretion (310 ± 732 vs 95 ± 185 mg/g Cr). These results suggested that the hypertensive patient who showed a morning rise in blood pressure had an advanced hypertensive cardiovascular complications.
