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Claus L. Petersen, Jytte Nielsen, Jamal A. Hanash, P-671: Elevated blood pressure in patients with hydronephrosis and unilateral renal dysfunction, American Journal of Hypertension, Volume 14, Issue S1, April 2001, Page 254A, https://doi.org/10.1016/S0895-7061(01)02001-5
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Abstract
Our intention has been to evaluate blood pressure in patients with hydronephrosis and substantial unilateral renal dysfunction in a population of patients with obstructive uropathy.
In accordance with clinical practice a consecutive sequence of 200 elective patients were referred to scinti-renography based on clinical suspicion of obstructive uropathy. Patients were included in the study if hydronephrosis was confirmed.
Patients with a clinical history of acute illness or pain were excluded.
The study group consisted of 137 patients who fulfilled scinti-renographic criteria of hydronephrosis. Mean age was 63 years. Eighty-five were males and 52 females.
Renography using 99mTc-DTPA tracer was performed on a general-purpose gamma camera. According to results of renography, based on standardized visual interpretation of the scintigram and tracer kinetic description of renal pelvic tracer transit time and the glomerular filtration rate (GFR), patients were categorized as hydronephrotic with substantial unilateral renal dysfunction or hydronephrotic without substantial unilateral renal dysfunction. Substantial unilateral dysfunction was defined as unilateral reduction in GFR of at least 50% compared to the contralateral kidney.
After 30 minutes rest in supine position, blood pressure was measured in an automated fashion using an oscillometric measuring unit (Omron HEM-705CP).
We measured systolic and diastolic blood pressure in patients (n=46) with hydronephrosis and unilateral dysfunction. (Hydro + unilat.dysfunc.) and compared results of blood pressure in patients (n=91) with hydronephrosis without unilateral dysfunction (Hydro - unilat.dysfunc.).
Mean systolic BP/Mean diastolic BP:
Hydro + unilat.dysfunc.: 141*/84 mmHg
Hydro - unilat.dysfunc.: 132 /82 mmHg
*) p=0.02
We conclude that systolic blood pressure is elevated in patients with hydronephrosis and unilateral renal dysfunction compared to patients with hydronephrosis without unilateral renal dysfunction.
