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Craig W. Belsha, P-628: Left ventricular mass in hypertensive children and adolescents at initial diagnosis, American Journal of Hypertension, Volume 14, Issue S1, April 2001, Page 240A, https://doi.org/10.1016/S0895-7061(01)01935-5
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Abstract
Left ventricular hypertrophy (LVH) may be an important marker of hypertensive target organ damage in children and adolescents. To evaluate the distribution of left ventricular mass in this population at diagnosis, all children < age 18 years with newly diagnosed hypertension who underwent M-mode echocardiography within 2 months of diagnosis since November, 1998 in an outpatient pediatric hypertension clinic were included in this retrospective analysis. Patients with a history of underlying structural cardiac disease were excluded. Measurements of left ventricular (LV) internal dimension in diastole, LV posterior wall thickness, and interventricular septum thickness were used for calculation of LV mass indexed for height2.7 (LVMI). Left ventricular hypertrophy was defined as LVMI > the 90th %tile for normal children and adolescents (36.69 gm/ht2.7for boys and 34.11 gm/ht2.7for girls).
We identified 26 children (18M), age 13.6 ± 2.8 y, with hypertension who had undergone echocardiography within 2 months of diagnosis. Most, 23, had essential hypertension, 3 had renal parenchymal disease. LVH was identified in 10 subjects (38%). Subjects with LVH did not differ from subjects without LVH by age, weight, or height. Distribution of LVMI is shown below: (See Table)
| LVMI %tile . | Frequency . | Percentage . |
|---|---|---|
| <50% | 8 | 30.8 |
| 50–89% | 8 | 30.8 |
| 90–94% | 3 | 11.5 |
| 95–99% | 4 | 15.5 |
| >99% | 3 | 11.5 |
| Total | 26 | 100.0 |
| LVMI %tile . | Frequency . | Percentage . |
|---|---|---|
| <50% | 8 | 30.8 |
| 50–89% | 8 | 30.8 |
| 90–94% | 3 | 11.5 |
| 95–99% | 4 | 15.5 |
| >99% | 3 | 11.5 |
| Total | 26 | 100.0 |
| LVMI %tile . | Frequency . | Percentage . |
|---|---|---|
| <50% | 8 | 30.8 |
| 50–89% | 8 | 30.8 |
| 90–94% | 3 | 11.5 |
| 95–99% | 4 | 15.5 |
| >99% | 3 | 11.5 |
| Total | 26 | 100.0 |
| LVMI %tile . | Frequency . | Percentage . |
|---|---|---|
| <50% | 8 | 30.8 |
| 50–89% | 8 | 30.8 |
| 90–94% | 3 | 11.5 |
| 95–99% | 4 | 15.5 |
| >99% | 3 | 11.5 |
| Total | 26 | 100.0 |
In summary, left ventricular hypertrophy may be present in a substantial percentage (38%) of children and adolescents at the time of initial diagnosis of hypertension.
