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Antonio J. Marinho-da-Silva, Guilherme M. Pego, Dina T. Rodrigues, Mercedes M. Alves, Luis C. Oliveira, Antonio M. Sa-e-Melo, Luis A. Providencia, P-622: Nondipper profile in repaired aortic coarctation, American Journal of Hypertension, Volume 14, Issue S1, April 2001, Page 238A, https://doi.org/10.1016/S0895-7061(01)01929-X
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Abstract
Background: A nondipper or otherwise extreme dipper profile it is of great importance in arterial hypertension evaluation, because this can help in risk stratification and eventual therapeutic options.
Coarctation of the Aorta (CoA) is a recognized secondary cause of arterial hypertension with surgical treatment. Despite blood pressure (BP) reduction and apparent normalization after surgical repair, some cardiovascular risk markers were previously identified in these patients and a particular clinical follow-up is mandatory,in order to avoid cardiovascular events. Our aim was to evaluate nocturnal decline (Nd) both in systolic (S) and diastolic (D) BP of successfuly CoA operated adolescents to achieve a better clinical profile definition of our patients.
Material and methods: Ambulatory 24 hours blood pressure monitoring was carried on in 46 adolescents operated on for CoA and presenting with equal or lower 95th percentile blood pressure level for sex and age. The percent Nd was estimated both for S and D blood pressure. A control group of 29 age matched normotensive adolescents (N) were submitted to the same protocol and identical Nd calculation.
Results: Relevant abnormalities were identified bettween the two groups with significant Nd both for S and D blood pressure(Table).
| . | CoA . | N . | p . |
|---|---|---|---|
| Nd S (%) | 8.4 ± 6 | 11.6 ± 4 | <0.05 |
| Nd D (%) | 15.1 ± 10 | 20.4 ± 5 | <0.02 |
| . | CoA . | N . | p . |
|---|---|---|---|
| Nd S (%) | 8.4 ± 6 | 11.6 ± 4 | <0.05 |
| Nd D (%) | 15.1 ± 10 | 20.4 ± 5 | <0.02 |
| . | CoA . | N . | p . |
|---|---|---|---|
| Nd S (%) | 8.4 ± 6 | 11.6 ± 4 | <0.05 |
| Nd D (%) | 15.1 ± 10 | 20.4 ± 5 | <0.02 |
| . | CoA . | N . | p . |
|---|---|---|---|
| Nd S (%) | 8.4 ± 6 | 11.6 ± 4 | <0.05 |
| Nd D (%) | 15.1 ± 10 | 20.4 ± 5 | <0.02 |
Conclusions: The less Nd in repaired CoA patients is identical to the nondipper profile often seen in other situations namely in severe forms of essential arterial hypertension. The meaningful of such abnormalities and its clinical relevance is still to be determined. However these results emphasises the needs for close follow-up of this young population.
