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Mario Biagini, Gianfranco Amodio, Gianfranco Antonelli, Maurizio Campaniello, Alessandro Rocchi, Fabrizio M. Morelli, P-510: Blood pressure response to exercise in normotensive young men with or without family history of hypertension, American Journal of Hypertension, Volume 14, Issue S1, April 2001, Page 201A, https://doi.org/10.1016/S0895-7061(01)01724-1
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Abstract
Many clinical studies suggest that blood pressure response to exercise may be predictable on one hand to the developing of hypertension in normotensive subjects with a family hystory of hypertension and, on the other hand, to the progression of the disorder in borderline hypertensives. The purpose of our study was to evaluate blood pressure response to exercise in young male normotensives with and without parental hystory of hypertension. Our study was carried out on 150 subjects belonging to Italian Air Force who met the following entry criteria: 1) age between 19 and 29 years; 2) no evidence of cardiac disease by hystory or physical exam; 3) normal routine E.C.G. The subjects were divided in two subgroups: A) Normotensives without family hystory of hypertension (92 sub); B) Normotensives having one or both parents with hypertension (58 sub).
All subjects underwent a submaximal bycicle exercise test with a load increase of 25 Watts every minute, until they reached 85% of the maximum predictable heart rate or until exhaustion. Besides we performed on each subject an echocardiographic exam and no significant difference between the two subgroups was observed.
The exercise test response, analized in the two subgroups showed the following results:
No difference in maximum workload and maximum heart rate reached;
No significant difference in systolic blood pressure at different stages of hypertension;
Subjects with family hystory of hypertension showed a significantly slower recovery of systolic blood pressure at third and fifth minute after the end of exercise.
Our data, consistent with previous results, seem to support the hypothesis that more than exercise, recovery blood pressure values may be suggestive of an exaggerated cardiovascular response, as expression of an enhanced cardiovascular reactivity to vasoactive substances mobilized during physical exercise.
Such abnormal cardiovascular reactivity seems to represent an early predictable index to the developing of the disease in young subjects with family hystory of hypertension who might need a specific prevention program.