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Daniela Degli Esposti, Nicola Venturoli, Maria Rosa Pugliese, Paolo Mazzetti Gaito, Angelo Ghirardini, Flavia Petrini, Alessandro Nanni Costa, Lorenza Ridolfi, Gerardo Martinelli, P-502: Prevalence of hypertension in a potential donors population, American Journal of Hypertension, Volume 14, Issue S1, April 2001, Page 199A, https://doi.org/10.1016/S0895-7061(01)01716-2
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Abstract
Cerebrovascular accidents, and cerebral hemorrhage in particular, are main causes of death among potential organ donors, wilst traumatic events are cause of death in a less percentage of donors. Being high blood pressure (HBP) a well known risk factor for cerebrovascular accidents, aim of this study was to assess its prevalence in a potential donors pool. In a three year period we studied a potential donors pool coming from a population of about 18 millions inhabitants. In this selected population we evaluated the presence of HBP relatively to different causes of death. Among 899 potential donors (538 M, 361 F, mean age 48 yrs, range 0-88) anamnestic HBP was globally present in 229 subjects (25.5%), of which 92 received antihypertensive treatment (40%). In 535 (59%) the cause of death was cerebrocardiovascular accident (CCV) (254 M, 278 F, mean age 57 yrs) and in 364 (40%) non-vascular events (NV) (276 M, 88 F, mean age 36). The subjects with CCV death were significantly older than those with NV death (p<.05). HBP was present in 211 (39%) of CCV deaths (mean age 61 vs 54 yrs of normotensive CCV deaths, n.s.) and in 18 (5%) of NV deaths (p<.001). 86 (41%) of hypertensive CCV deaths and 6 (33%) of hypertensive NV deaths received antihypertensive treatment (n.s.). In conclusion the prevalence of HBP was globally high in our population of potential donors, considering the relatively young age of subjects. However, HBP was more frequently present among CCV deaths. NV potential donors were significantly younger respect to CCV, which could justify the lower prevalence of HBP among these subjects. The difference in prevalence of HBP between CCV and NV potential donors is anyway significant, therefore confirming HBP as an important cause of fatal cerebrovascular accidents. Moreover antihypertensive treatment was referred only in 40% of subjects, underlining the non optimal management of this cardiovascular risk factor.
