Abstract

To Study the relationship between UNa, UK, UCa, UCr, and blood pressure. An epidemiological survey was performed in 200 local residents of 20-59 years old from 16 regions of China. An age-sex stratified random sample was draw. 3248 persons were divided into five age-sex specific groups. Health status was assessed by a questionnaire. Height and weight were measured. The blood pressure was measured and A night Urine was collection for analysis sodium, potassium, calcium and creatinine and the excretion of per eight hours.

A striking statistically significant difference exists in UNa, UNa/K ratio between hypertensive group and normal BP group (UNa 67.8mEq,UNa/k ratio 8.3 and UNa 54.5mEq, UNa/k ratio 7.3 respectively, P<0.01). But no statistical significance was found between south and north or sex in hypertensive groups. The inter population simple correlation and regression analysis showed a negative relationship between UCa/Cr or UK/Cr and SBP. The level of UNa did not correlate with BP. A positive correlation was found between UNa/Cr or UNa/K ratio and SBP or DBP for intra-individual but negative correlation was found between UK/Cr or UCa/Cr and SBP or DBP.

The study showed that dietary salt intake is a contributor to blood pressure elevation and to the prevalence of hypertension. Lifestyle modifications should be instituted including reduction of high salt intake, and increase in potassium, Calcium intake.

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