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G. P. Vyssoulis, E. A. Karpanou, J. D. Barbetseas, S. S. Castellanos, J. K. Rizos, A. E. Giannakopoulou, D. A. Belegrinos, P. K. Toutouzas, P-400: Left atrial and aortic root dimensions but not function are related in arterial hypertension, American Journal of Hypertension, Volume 14, Issue S1, April 2001, Page 165A, https://doi.org/10.1016/S0895-7061(01)01558-8
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Abstract
Left atrial (LA) and aortic root (AO) dimension increase is a function of age, while arterial hypertension augments chamber enlargement.
To explore their relationships over time, we studied 9835 consecutive untreated patients with uncomplicated essential hypertension. On echocardiographic examination, LA and AO were measured, their indices were obtained by dividing with body surface area as LAI and aortic systolic diameter index (AOSI), and with simultaneous blood pressure measurements aortic root distensibility (ARD) and stiffness (ASI) were calculated. LAI increased with advancing decade of age (15.0, 16.6, 18.1, 19.4, 22.8 mm/m2, r=0.67), as did AOSI (17.1, 18.0, 18.6, 19.2, 20,4 mm/m2, r=0.45), while ARD (10.6, 7.5, 5.4, 3.9, 2.6 cm2/dyne r=-0.73) decreased and ASI (5.5, 7.8, 11.2, 15.1, 22.6, r=0.79) increased with age. The relationship of LAI to AOSI was strong (r=0.58) even after correcting for age (r= 0.42) while its relations to ARD and ASI were better (r=-0.53 and 0.61), but became weak after age correction (r=-0.08 and 0.19).
It is concluded that AO and LA dimensions increase in parallel with advancing age in arterial hypertension, while AO function deteriorates more rapidly.
