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Z. Q. Liu, J. Yang, J. J. Mu, Y. M. Liang, Y. X. Wang, D. J. Zhu, C. F. Sun, T. Ye, P-345: Adding potasium and calcium to the dietary salt as a hypertension- preventive approach in adolescents with higher blood pressure and their family members: A single blind random-controllized trial, American Journal of Hypertension, Volume 14, Issue S1, April 2001, Page 145A, https://doi.org/10.1016/S0895-7061(01)01941-0
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Abstract
To investigate hypertension-preventive effects of adding potassium and calcium to the diet-salt in adolescents with higher blood pressure(HBP) and their family members, 330 adolescents with HBP (age: 22±3 yrs), selected from 4623 subjects who were followed up for 8 years, were enrolled, as well as the related 300 families with 651 family members. It was randomly divided into 3 groups: Adding K and Ca group (A), equally 10 mmol of potassium and calcium per person daily were added to the dietary salt; Restricting-salt group (R), the salt intakes gradually decreased, the goal was less 50~100 mmol per day than before and the control group (C). The salt was supplied freely for all the groups, in addition of K and CA in group A It was followed up every 6 months for two years, the follow-up rate was 87.4% for adolescents, 81.8% for the family members. The results show: (1) After two years the blood pressure (BP) in A, compared with the baseline, decreased average 5.9/2.8 mmHg (P<0.01), especially for the salt-sensitivity(SS), 9.9/5.5 mmHg (SS, n=37) vs 3.6/1.1 mmHg (non-SS, n=64), P<0.01; In group R, the salt intakes from average 3 days retrospective investigation decreased 54 mmol per day than before and the BP decreased 5.8/1.0 mmHg, but in the controls the BP increased 1.3/1.4 mmHg. (2) The BP in the family members also decreased average 5.4/3.4 mmHg in A, 5.6/2.4 mmHg in R, but it was increased 1.1/0.9 mmHg in the controls. In conclusion: adding potassium and calcium in the dietary salt can decrease BP in adolescents with HBP, especially for the salt sensitivity.
