Abstract

Objective

Informant reports of daily functioning are often useful when assessing functional skill impairments in neuropsychological dementia evaluations, given potential biases with self-reporting from low insight and/or a reluctance to endorse reduced independence. Two measures of informant functional skill assessments were compared within patients relative to their objective neurocognitive performances.

Method

Participants included 19 (32% male, 68% female; 21% Hispanic, 69% Caucasian) outpatient older adult dementia evaluations aged 60 to 90 years (Mean age = 74, SD = 7.7) who were accompanied by a family member or caregiver informant. The Activities of Daily Living Questionnaire (ADLQ) and the Lawton Activities of Daily Living and Instrumental Activities of Daily Living Scale (ADL/IADL) informant reports were compared relative to performances on the Hopkins Verbal Learning Test delayed recall trial (HVLT), Trail Making Test Part B (TMTB), CLOX: An Executive Clock Drawing Task (CLOX1), and the Controlled Oral Word Association Test, FAS and Animals (COWAT).

Results

Simple linear regression analyses indicated the ADLQ significantly predicted both TMTB (β = −.52, 95% CI [−.81, −.23], p < .01; R2 = .47) and HVLT (β = −.38, 95% CI [−.67, −.08], p < .01; R2 = .31) performances. The ADL/IADL scale significantly predicted TMTB performances (β = −.70, 95% CI [−1.1, −.30], p < .01; R2 = .46). A significant correlation was observed between ADLQ and ADL/IADL informant reports (r(17) = .60, p < .01).

Conclusion

There was a significant linear relationship between both ADLQ and ADL/IADL informant reports with TMTB performances. The ADLQ reports also significantly predicted HVLT performances. No significant relationships were observed between either ADLQ and ADL/IADL reports, and participants’ CLOX1 or COWAT FAS/Animals performances.

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