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Authors: Nicholas C Spies
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Journal Article

Large Language Models Lack Sufficient Performance to Provide Definitive Regulatory Guidance Get access

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Ryan C Shean and others
The Journal of Applied Laboratory Medicine, jfaf047, https://doi.org/10.1093/jalm/jfaf047
Published: 18 April 2025
Journal Article

Prospective and External Validation of an Ensemble Learning Approach to Sensitively Detect Intravenous Fluid Contamination in Basic Metabolic Panels Get access

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Nicholas C Spies and others
Clinical Chemistry, Volume 71, Issue 2, February 2025, Pages 296–306, https://doi.org/10.1093/clinchem/hvae168
Published: 15 November 2024
Journal Article

Validating, Implementing, and Monitoring Machine Learning Solutions in the Clinical Laboratory Safely and Effectively

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Nicholas C Spies and others
Clinical Chemistry, Volume 70, Issue 11, November 2024, Pages 1334–1343, https://doi.org/10.1093/clinchem/hvae126
Published: 10 September 2024
Journal Article
EDITOR'S CHOICE

Cardiac Troponin to Adjudicate Subclinical Heart Failure in Diabetic Patients and a Murine Model of Metabolic Syndrome

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Hannah M Brown and others
The Journal of Applied Laboratory Medicine, Volume 9, Issue 6, November 2024, Pages 913–926, https://doi.org/10.1093/jalm/jfae091
Published: 03 September 2024
Journal Article

Automating the Detection of IV Fluid Contamination Using Unsupervised Machine Learning

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Nicholas C Spies and others
Clinical Chemistry, Volume 70, Issue 2, February 2024, Pages 444–452, https://doi.org/10.1093/clinchem/hvad207
Published: 12 December 2023
Journal Article
EDITOR'S CHOICE

Generalizability of a Machine Learning Model for Improving Utilization of Parathyroid Hormone-Related Peptide Testing across Multiple Clinical Centers

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He S Yang and others
Clinical Chemistry, Volume 69, Issue 11, November 2023, Pages 1260–1269, https://doi.org/10.1093/clinchem/hvad141
Published: 21 September 2023
Journal Article

GPT-4 Underperforms Experts in Detecting IV Fluid Contamination

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Nicholas C Spies and others
The Journal of Applied Laboratory Medicine, Volume 8, Issue 6, November 2023, Pages 1092–1100, https://doi.org/10.1093/jalm/jfad058
Published: 13 September 2023
Journal Article

Asymptomatic Hyponatremia and Hyperkalemia in a Patient with Leukemic Leukocytosis

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Zita M L Hubler and others
Clinical Chemistry, Volume 69, Issue 11, November 2023, Pages 1322–1323, https://doi.org/10.1093/clinchem/hvad105
Published: 09 September 2023
Journal Article

Data-Driven Anomaly Detection in Laboratory Medicine: Past, Present, and Future

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Nicholas C Spies and others
The Journal of Applied Laboratory Medicine, Volume 8, Issue 1, January 2023, Pages 162–179, https://doi.org/10.1093/jalm/jfac114
Published: 04 January 2023